When the above-listed significant variables were converted to categorical variables using cut-off values, malignancy (OR: 2.17, 95% CI: 1.13–4.17, p = 0.021), respiratory rate ≥24 breaths/min (OR: 2.18, 95% CI: 1.24–3.82, p = 0.007), heart rate ≥100 beats/min (OR: 2.92, 95% CI: 1.68–5.08, p < 0.001), albumin ≤3.09 g/dL (OR: 3.85, 95% CI: 2.09–7.07, p < 0.001), lactate >1.7 mmol/L (OR: 2.59, 95% CI: 1.53–4.38, p < 0.001) and NT-ProBNP >500 pg/mL (OR: 2.23, 95% CI: 1.26–3.95, p = 0.006) were significant prognostic factors in patients with CAP (Table 5). This evidence concerns the gene NPPB and cancer.