To confirm the observed phenotype across additional GBM subtypes, we generated CRISPR-Cas9 population TEAD1 and TEAD4 knockouts in three additional primary GBM cell lines, G-13306, G-12746, and G-16302 (Supplementary Fig. 5d), representing various GBM molecular subtypes (Supplementary Table 1). Here, TEAD1 is linked to glioblastoma.