Infection with L. major LV39 resulted in similar ear lesion diameters and cervical lymph node parasite loads between KRT14cre IL-4Rα−/lox BALB/c and littermate control IL-4Rα−/lox BALB/c mice, with the surprising exception of significantly reduced parasite loads in the ear (Fig. 4B). This evidence concerns the gene IL4R and infection.