GPT and chronic kidney disease: The pooled data showed that the early-CKD group had similar ALT elevation rates (30/750, 4.00%) as the advanced-CKD group (10/162, 6.17%) (RR, 0.730; 95% CI, 0.295 to 1.807); in addition, no significant difference was observed (RR, 1.460; 95% CI, 0.18 to 12.03) between the early-CKD group and the dialysis group.