NFKB1 and ovarian cancer: An unexpected observation made by our group revealed that inhibition of NF-κB in a syngeneic mouse model of ovarian cancer, increased pro-tumorigenic M2 macrophages, which promoted ascites, an increased expression of pro-tumorigenic soluble factors (such as VEGF in ascites fluid), and an infiltration of more M2 macrophages into the TME [48,72].