To further understand the role of this CAM in regulating cancer metastasis, other future experiments may include: (a) searching for the heterophilic ligands or partners of METCAM/MUC18 [9], (b) systematic investigation of the three mechanisms in the tumor and metastasis dormancy (for examples, what are the key members involved in intrinsic growth inhibition, immunological suppression, and/or reducing angiogenesis)? The gene discussed is MCAM; the disease is neoplasm.