The fourth novel aspect is that a tumor and metastasis suppressor role played by human METCAM/MUC18 in the malignant propensity of human ovarian carcinoma cells and other cancer cell lines appears to suggest the probability that METCAM/MUC18 may trigger on tumor dormancy [37], which is intriguing for future research. The gene discussed is MCAM; the disease is ovarian carcinoma.