Although AKAP9, PDE4DIP, and CDK5RAP2 are known to anchor the PKA holoenzyme at the Golgi apparatus and centrosome to facilitate microtubule organization [31], this work characterizes the interaction of these proteins with PKA as Fyn-mediated, and demonstrates that Fyn exists in complex with PKA and these AKAPs in a glioblastoma line (Figure 7A). This evidence concerns the gene CDK5RAP2 and glioblastoma.