ITGAM and infection: Flow cytometry analysis of lungs at 3dp.i., the septic phase of infection exhibiting peak neutrophil accumulation [11, 14, 45], showed that the number of CD11b+Ly6G+ neutrophils was significantly reduced in KPn infected mice upon Nec1s treatment as compared to untreated or vehicle treated KPn infected mice (Fig 8A and 8A’).