This was carried out by using one of two MDAs [nocodazole (NOC) and 2-methoxyestradiol (2-MeO-E2)] or a DDA [camptothecin (CPT)] and human acute leukemia Jurkat T cell clones stably transfected with an empty vector (J/Neo) or the BCL-XL expression vector (J/BCL-XL) that causes the overexpression of anti-apoptotic BCL-XL [25]. This evidence concerns the gene BCL2L1 and acute leukemia.