Also, when frozen human lung cancer tissue slides were stained with anti-mouse FN-Alex 488(green), anti-human CD163 (blue) and nuclear dye-SiR-DNA(red), we found that there had significantly increased FN expression in the area where macrophages were clustered in the inflammation areas around lung cancer (Figure 1(c,d)). This evidence concerns the gene FN1 and lung carcinoma.