RPL3L and atrial fibrillation: We found two novel genome-wide significant atrial fibrillation associations in the gene RPL3L on chromosome 16, with the missense variant p.Ala75Val (allele frequency 3.65% in Iceland, OR: 1.19, P = 3.4 × 10−12) and the splice-donor variant c.1167+1G>A (allele frequency 0.61% in Iceland, OR: 1.52, P = 8.2 × 10−10).