TNF and Salmonella Infections: In mouse peritoneal MΦs, Salmonella infection up-regulated the expression of both of M1 MΦ markers (CCR7 and CD86), M2 MΦ marker (CD163 and CD206) and induced the secretion of M1 MΦ marker TNF-α and M2 MΦ marker IL-10 in ascitic fluid significantly (Figures 7C,D).