Due to the fact that iNPH and AD can coexist histopathological analysis was performed, and brain biopsies divided into three groups according to the presence or absence of amyloid plaques and NFT (Aβ−/tau−, Aβ+/tau−, Aβ+/tau+) (Material and methods, Table 1 and Additional file 1: Figure S1). Here, MAPT is linked to Alzheimer disease.