CD4 and cancer: Previously, MCM has been shown to exert an apoptotic effect against human LNCaPprostate cancer cells in vitro11 and to activate NK cells in humans post ingestion.1 In our study, MCM enhanced the cytotoxic effect of DC-CD8+ T cells andstimulated DCs to prime CD4+ T cells and secrete significant amounts of IFN-γ, allof which are known to exert antitumor activity.12 Taken together, these results suggest that MCM exerts its anti-canceractivity by mounting different arms of the immune system.