The results of the study showed that tumour tissue of untreated patients had higher expression of FPGS, GGH, MTHFD1L, and SLC19A1/RFC-1 compared with mucosa, whereas expression of ABCC3/MRP3 and SLC46A1/PCFT was higher in mucosa compared with tumour. The gene discussed is MTHFD1L; the disease is neoplasm.