More recent data suggest that the delay to acromegaly diagnosis is now reduced to 3–6 years, a reduction that may be attributed to improved GH and IGF-1 assays, increased use of magnetic resonance imaging for the assessment of head-related complaints, increased acromegaly awareness among endocrinologists, and the increased availability of information to patients in the internet era [14–17]. The gene discussed is GH1; the disease is acromegaly.