It correlated with AST/ALT ratio, blood coagulation time, and albumin levels in both the MHE (r = 0.657, P = 0.001; r = 0.633, P = 0.001; r = −0.555, P = 0.001 for AST/ALT, blood coagulation time, and albumin levels, respectively) and No-HE groups (r = 0.497, P = 0.003; r = 0.578, P = 0.006; r = −0.448, P = 0.042 for AST/ALT, blood coagulation time, and albumin levels, respectively). This evidence concerns the gene ALB and hereditary elliptocytosis.