CAV1 and schizophrenia: However, caveolin-1 (Cav1), which encodes a major component of caveolae, also has caveolae-independent functions (Echarri and Del Pozo, 2015, Gioiosa et al., 2008, Head and Insel, 2007, Takayasu et al., 2010, Trushina et al., 2006a) and is reported as a risk gene for schizophrenia (Allen et al., 2011, Kassan et al., 2017).