The levels of IFN-γ, IL-1α, IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12, IL-13, IL-15, IL-17, CCL2, and VEGF were significantly higher in the NVG eyes than in the normal control eyes, and IL-1β, IL-2, IL-5, IL-6, IL-8, IL-10, IL-12, IL-13, IL-15, IL-17, CCL2, and VEGF were higher than in the POAG eyes. Here, IL1B is linked to open-angle glaucoma.