In POAG eyes, IL-1α, IL-2, IL-10, IL-12, IL-17, and TNF-α were positively correlated with the visual field (IL-1α (ρ = 0.60, P = 0.0004), IL-2 (ρ = 0.41, P = 0.0238), IL-10 (ρ = 0.46, P = 0.0101), IL-12 (ρ = 0.53, P = 0.0024), IL-17 (ρ = 0.40, P = 0.0271), and TNF-α (ρ = 0.44, P = 0.0159)). Here, TNF is linked to open-angle glaucoma.