By further analysis of the two different subtypes of GCB-DLCBL, we detected a similar cytoplasmic NR4A1 extent in primary (de novo) GCB-DLCBL (pGCB-DLBCL) as compared to the transformed subtype (tGCB-DLBCL) (on average 41.7% vs. 52.4%, p = 0.19, Fig. 1d). This evidence concerns the gene NR4A1 and diffuse large B-cell lymphoma.