By stratifying the patient cohort into two groups using the median percentage of lymphoma cells (median = 40%) exhibiting a cytoplasmic NR4A1 staining (as opposed to nuclear or no NR4A1), a significant association between high cytoplasmic NR4A1 level and favourable cancer-specific survival was observed (n = 60, p = 0.016, log-rank test, Fig. 1e). Here, NR4A1 is linked to cancer.