Analyses were set in relation to the staining pattern of NR4A1 and DLBCL subtype on selected cases with either extremely low cytoplasmic NR4A1 (below 20%, n = 9 consisting of 6 NGCB- and 3 GCB-DLBCL) or high cytoplasmic NR4A1 (above 80%, n = 8 consisting of 2 NGCB- and 6 GCB-DLBCL). This evidence concerns the gene NR4A1 and diffuse large B-cell lymphoma.