Toward this end, we induced prostatitis in Nkx3.1 wild-type or mutant mice using CP1 bacteria, which had been isolated from the prostate of a patient with prostatitis and therefore likely to represent a clinically relevant model of prostatic inflammation (Rudick et al., 2011; Simons et al., 2015). This evidence concerns the gene NKX3-1 and male reproductive organ cancer.