In pancreatic cancer, linc-ROR confers gemcitabine resistance at least partly via inducing autophagy, and further research reported a linc-ROR/miR-124/PTBP1/PKM2 axis that involved in the regulation of gemcitabine resistance in pancreatic cancer cells [84]. The gene discussed is PTBP1; the disease is familial pancreatic carcinoma.