The effect of Trichinella spiralis on a melanoma model based on a subcutaneous injection of B16-F10 cells has been described within the immunotherapy with biological agents, where the previous oral infection with L1 larva of T. spiralis decreased tumor growth and its metastasis to the lungs by reducing the production of some chemokines, such as CXCL9, CXCL10, CXCL1, CXCL13, and IL-4 [30]. The gene discussed is CXCL10; the disease is melanoma.