BCL2 and familial pancreatic carcinoma: Inhibition of the anti‐apoptotic Bcl‐2 members by the early generation BH3 mimetics, BH3I‐2′ and HA14‐1, was associated with global and sustained Ca2+ responses induced in normal mouse PACs and in the rat pancreatic cancer cell line AR42J (Gerasimenko et al.,2010).