A hit from a screen to discover small molecule inhibitors of virus infection identified the adamantyl diphenyl piperazine 3.3 as an inhibitor of transduction of Vero cells by murine leukemia virus (MLV) particles pseudotyped with LASV GP (IC50 = 1.8μM ± 1.3), but not of transduction by MLV particles pseudotyped with GPs from the related Old World arenaviruses lymphocytic choriomeningitis virus (LCMV) Armstrong, LCMV WE, LuJo virus (LUJV) or with Junin virus (JUNV), Ebola virus (EBOV) or vesicular stomatitis virus (VSV) (Fig 1A). Here, NBEAL2 is linked to viral infectious disease.