BRCA1 and ovarian cancer: In another study performed by Cherbal et al. [10], over 101 individuals from 79 breast and ovarian cancer families were examined for unclassified variants (UVs) and polymorphisms in the BRCA1 and BRCA2 genes by Single-strand conformation polymorphism (SSCP) or High-Resolution Melting (HRM) curve analysis, followed by direct sequencing.