To gain a mechanistic understanding relative to the upregulated expression of CB1 gene in DMD muscles, and to define the specific muscle cell subpopulation responsible for these changes, we performed RNA-sequencing (RNA-seq) experiments on fluorescence-activated cell sorting (FACS)-sorted satellite, macrophage and fibroadipogenic progenitor (FAP) cells freshly isolated from the hind limb muscles of 8-week-old control and mdx mice. The gene discussed is CNR1; the disease is Duchenne muscular dystrophy.