Specifically, the red cluster contains 10 of the active TB patients, 14 LTBI patients and 2 controls and features very high levels of FGF-2, IFN-γ, IL-5, IL-6, IL-7, IL-17A, IP-10, TGF-α, TNFα and VEGF (cluster 1) and high levels of PDGF-BB, PDGF-AA and Gro (cluster 3). This evidence concerns the gene TNF and tuberculosis.