Furthermore, analysis of genes associated with risk of other inherited neoplastic syndromes different to HBOC identified heterozygous pathogenic variants for MSR1 (4%, 2/52), LIG4 (4%, 2/52) and PDE11A (6%, 3/52) in the affected women in both groups (Figure 1 and Figure 2, Table 3). The gene discussed is PDE11A; the disease is neoplastic syndrome.