CD4 and inflammatory bowel disease: As shown in Figure 2, no significant changes were detected in the expression levels of the Fos family (c-Fos, FosB, Fra-1, and Fra-2) (Figure 2A–D), Jun family (c-Jun, JunB, and JunD) (Figure 2E–G), and REST (Figure 2H) transcripts in the CD4+CD25− T cells of the IBD model mice.