RAC1 and ovarian serous adenocarcinoma: Rac1 GEF and GAP regulatory factors are mutant or exhibit altered expression in ovarian serous adenocarcinoma with a frequency of 0.3–1.6% based on our analyses of 28 relevant regulatory proteins in COSMIC v86 [144] and the cBioPortal platform for TCGA data viewing [19,131] (Figure 4 [20,83,118,138,144,145,146,147]).