Since APC, FOXA1 and RASSF1A were biomarkers common to BrC, CRC and LC, they were further tested as gene panel for cancer detection (designated “PanCancer”), whereas RARβ2, SCGB3A1, SEPT9 and SOX17 were considered a gene panel for discrimination of primary cancer localization (“CancerType” panel). This evidence concerns the gene SOX17 and cancer.