Animals that were pre-treated with PTH for 5 days prior to tumour cell injection had significantly higher total numbers of skeletal tumours compared to animals receiving PBS (Figure 6A, mean numbers of tumours/mouse: 40 μg/kg PTH: 5.71 vs. control: 2.57, p < 0.0001 and 80 μg/kg PTH: 5.25 vs. control 2.57, p < 0.001). Here, PTH is linked to neoplasm.