Given the close relationship between OxSt and cardiovascular-renal remodeling, that studies from our laboratory have demonstrated using markers of OxSt and proteins related to OxSt such as p22phox, lipoperoxides and RhoA/Rho kinase pathway [14,18], we thought it would be of interest to examine the status of OxSt in patients with Fabry disease and its relationship to proliferative/remodeling processes at cardiovascular level. Here, CYBA is linked to Fabry disease.