LYZ and irritable bowel syndrome: The lysozyme gene (LYZ) (VPR vs IBS) on BTA 5, encodes for the 1,4-beta-N-acetylmuramidase C. It belongs to a class of enzymes that lyse the cell walls of certain gram-positive bacteria and has also been described in other important functions including inactivation of certain viruses, enhancement of phagocytic activity for leukocytes and macrophages, and control of inflammation [24].