Also, a large body of evidence indicates that TNF‐α, IL‐1β, IFN‐γ, IL‐6, IL‐8, eotaxin, and RANTES are involved in recruitment and activation of macrophages, neutrophils, eosinophils, basophils, monocytes, and NK‐cell to the sites of endometriosis, thus promoting inflammatory changes and enhance angiogenesis through increase production of VEGF (Reis et al., 2013). This evidence concerns the gene CCL5 and endometriosis.