TGFB1 and gastric cancer: To address this issue in more detail, we performed PCR array analysis and found that FZD7, CDH2, TGFB1, SPARC, ITGA5, and ZWB1 mRNAs were overexpressed in concert with SUSD2. These findings implicate the contribution of the WNT signaling pathway to the malignant phenotype of GC.