For example, SUSD2 increases the invasiveness of breast cancer cells and may act as a component of the mechanism of immune evasion through induction of apoptosis of the Jurkat T cell line.14SUSD2 recruits macrophages into the tumor microenvironment, and promotes M2 polarization, indicating that inhibiting the function of SUSD2 may serve as an effective therapy for patients with breast cancer.16 Here, SUSD2 is linked to neoplasm.