A study of [18F]ML-10 [9] — a member of the aposense family of biomarkers that measures ‘apoptotic imprint’ — in human subjects reported favourable dosimetry and biodistribution, and binding to apoptotic sites in testicular tissue of mice, confirmed by terminal deoxynucleotidyl transferase (TdT) dUTP nick-end labeling (TUNEL) of apoptotic cells; initial studies reported correlation of early changes of tumour [18F]ML-10, and later changes in anatomical tumour dimension following radiotherapy [16, 17]. This evidence concerns the gene DNTT and neoplasm.