NFKB1 and inflammatory bowel disease: Some studies point to the use of some common immunological pathways, including regulation of both NF-κB and PPARγ, since commensal microbiota, which can be involved in IBD pathogenesis in the presence of epithelial barrier dysfunction and increased intestinal permeability and may also influence the activation of and can also regulate the activation of both pathways [99, 100]; consequently, further studies are required to clarify this aspect.