It has been associated with pathological processes of fibrosis and cancer progression requiring epithelial cell migration (Lamouille et al., 2014), and responsible for tight junctions by gaining mesenchymal markers such as N-Cadherin, Vimentin, Fibronectin, and TG2-Snail-E-cadherin axis (Rout-Pitt et al., 2018). This evidence concerns the gene SNAI1 and cancer.