CD8A and infection: While we detected reduced numbers of virus-specific CD8+ T cells in the early acute phase of infection this did not translate into any detectable impairment of the early memory or humoral responses at day 28 p.i. However, while day ~30 p.i. represents a useful time to examine early memory responses to primary IAV infection in adult mice (Wu et al., 2014), the kinetics and magnitude of these responses might be different in juvenile mice, requiring more thorough characterization.