Whereas C5aR1 expression was significantly increased in all CAD subgroups compared to healthy controls with the highest levels in the STEMI patients (Figure 5A), the increase in C5aR2 and C3aR were more moderate, showing significantly increased levels as compared with controls in the STEMI group (C5aR2) and NSTE-ACS group (C3aR) only (Figures 5B,C). Here, C5AR1 is linked to coronary artery disorder.