After evaluating gene, protein and miRNA expression, using correlation analysis, the results show that miR-29b-3p, miR-29c-3p, miR-199a-5p, and miR-532-3p might be candidates to repress GLUT4 and HK2 expression, which could contribute to glycemic homeostasis impairment in diabetes. This evidence concerns the gene SLC2A4 and diabetes mellitus.