LGALS3 and myeloid sarcoma: Gal-3 expression increases in active human MS lesions (Stancic et al., 2011), in periventricular regions in human MS and after murine TMEV infection (James et al., 2016), whereas Gal-3 loss reduces the number of immune cells in the SVZ and restores proliferation in a viral model of MS (James et al., 2016).