SMAD5 and gastric cancer: According to the mRNA expression data of different types of GC from cBioPortal, significant differences were observed between EBVaGC and EBVnGC for GDF5, CXCL10, SMAD5 and PTGER3 (P < 0.001, P < 0.001, P = 0.002 and P < 0.001).