In multivariate Cox proportional hazards analysis adjusted for age, sex, body mass index (BMI), serum creatinine, estimated glomerular filtration rate (eGFR), HDL-C, hemoglobin (Hb), blood glucose, hs-CRP, NT-proBNP, SBP, smoking, family history of premature CAD, history of hypertension and diabetes mellitus, high H-FABP level was still an independent prognostic risk factor for CV events (HR 2.93, 95% CI 1.95–4.394, p < 0.001). The gene discussed is NPPB; the disease is Hypertension.