This is in line with results from unpublished GWASs of AD in which AD-associations of variants near the MEF2C and FERMT2 genes were not replicated [52, 53] (p = 5.4 × 10−3, [52] p = 3.0 × 10−4 for MEF2C [53] and p = 1.6 × 10−5 for FERMT2 [53] variant, with 5.0 × 10−8 being the genome-wide significance threshold). Here, MEF2C is linked to Alzheimer disease.