The unbiased approach showed that expression of ALOX5 and ALOX12B are significantly higher in “high” expressing group, compared to the “low” expressing group, in the TCGA ovarian tumor cohort (n = 216; ALOX5 p = 0.00108 and ALOX12B p = 0.00248) as well as in other tumor cohorts (Fig. 6h and Supplementary Figure 6h–n). Here, ALOX5 is linked to neoplasm.