NKX2-1 and non-small cell lung carcinoma: Previous RNA-sequencing analyses of non-small cell lung carcinomas (NSCLCs) have shown that NKX2-1-AS1 is highly expressed in primary lung adenocarcinomas compared to squamous carcinomas11,21,23 and in some small cell carcinomas24, a pattern of expression that is similar to that of the adjacent protein-coding gene NKX2-1.