NKX2-1 and neoplasm: These data indicate that the overall pattern of expression of NKX2-1-AS1 mature transcript is similar to that of NKX2-1 in normal and tumor tissues and cell lines, but that the relative expression levels of these genes vary among specimens, and that increased levels of expression of NKX2-1-AS1 in certain lung tumors is not explained by locus amplification.