APOE and early-onset autosomal dominant Alzheimer disease: Given that enlargement of lateral ventricles has been suggested in Alzheimer’s disease, we examined the association of APOE alleles and found no association between the APOE ɛ4 (p-value = 0.86) or APOE ɛ2 (p-value = 0.81) and lateral ventricular volume in our study population.